Product Information
Silvestrol is a natural product with broad-spectrum antiviral. Furthermore, Silvestrol is an anti-cancer compound that is a potent and selective inhibitor of cyclin-dependent kinases, for example, eIF4A. It inhibits the proliferation of cancer cells by blocking their energy metabolism, inhibiting the production of ATP and glutathione (GSH). Silvestrol has been shown to have minimal toxicity in animal studies and can be used as an antitumor agent. It inhibits the Mcl-1 protein, which is a regulator of apoptosis, leading to tumor cell death. Silvestrol also has been shown to induce cell cycle arrest at G2/M phase in human tumor cells without affecting normal cells. The cyclin D2 gene, which is overexpressed in many cancers, may be a target for silvestrol treatment.
Chemical properties
Technical inquiry about: 3D-FS175699 Silvestrol
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