Salsalate

CAS: 552-94-3

Ref. 3D-FS27786

Product Information

• Name: Salsalate
• Synonyms: Salicylic acid salicylate2-Hydroxybenzoic acid 2-carboxyphenyl ester, 2-((2-Hydroxybenzoyl)oxy)benzoicacid, 2-(2-Hydroxybenzoyl)oxybenzoic acid, 2-(2-Hydroxybenzoyloxy)benzoic acid, 2-Hydroxybenzoic Acid 2-Carboxyphenyl Ester, 2-Salicylsalicylic Acid, 2-[(2-Hydroxybenzoyl)Oxy]Benzoic Acid, 2-{[(2-Hydroxyphenyl)Carbonyl]Oxy}Benzoate, Amigesic, Benzoate, 2-Hydroxy-, 2-Carboxyphenyl, Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester, Diacesal, Diagen, Diplosal, Disalcid, Disalgesic, Disalicylic acid, Disalyl, Mono-Gesic, Nobacid, Nsc 49171, Salflex, Salgesic, Salical, Salicyl salicylate, Salicylic acid, bimol. ester, Salicylic acid, salicylate, Salicylosalicylic acid, Salicyloxysalicylic acid, Salicyloylsalicylic acid, Salicylsalicylic acid, Salina, Salsalat, Salsalato, Salsitab, Salysal, Sasapirin, Sasapyrine, Sasapyrinum, o-Salicylsalicylic acid

Description

Salsalate is a nonsteroidal anti-inflammatory drug that belongs to the class of drugs known as salicylates. It is used to treat chronic arthritis and osteoarthritis. Salsalate inhibits the production of inflammatory mediators such as prostaglandins and cytokines, thereby reducing inflammation and pain. The mechanism of action has been shown in experimental models, which indicates that salsalate may inhibit transcriptional regulation, protein synthesis, or DNA replication. Salsalate also inhibits the production of cholesterol by binding to fatty acids in adipose tissue. This drug has been shown to reduce hepatic steatosis and prevent liver damage caused by nonsteroidal anti-inflammatory drugs (NSAIDs). Salsalate binds with high affinity to hydrogen bonding interactions with dimethyl fumarate, a drug used for treatment of multiple sclerosis (MS).

• Brand: Biosynth

Chemical properties

• Molecular weight: 258.23 g/mol
• Formula: C₁₄H₁₀O₅
• Purity: Min. 95%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
• InChI key: InChIKey=WVYADZUPLLSGPU-UHFFFAOYSA-N
• SMILES: O=C(Oc1ccccc1C(=O)O)c1ccccc1O