N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

Ref. 3D-FS27894

Product Information

• Name: N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate
• Synonyms: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide esterNSC 344483SMCC, (2,5-Dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate, 1-[(4-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-, 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexancarboxylate, 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate, 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester, 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester, Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester, N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate, N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate, N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate, N-Succinimidyl4-(N-maleimidomethyl)cyclohexane-1-carboxylate, NSC 344483, Smcc, Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate, Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate, Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate, Trans-4-(Maleimidomethyl)Cyclohexanecarboxylic acid-NHS
• CAS: 64987-85-5

Description

N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate (SMCC) is a monoclonal antibody that is used as an immunoconjugate to target tumors. SMCC is a covalent linker that attaches to the CD1a molecule on the surface of mouse cells. This attachment leads to the production of antibodies against CD1a, which are then used to target tumor cells. SMCC is also used for diagnosis and prognosis by attaching to epidermal growth factor receptor (EGFR). It can be used in conjunction with platinum-based chemotherapy, such as cisplatin and carboplatin, for bladder cancer treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 334.32 g/mol
• Formula: C₁₆H₁₈N₂O₆
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
• InChI key: InChIKey=JJAHTWIKCUJRDK-UHFFFAOYSA-N
• SMILES: O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1