Sulbutiamine

CAS: 3286-46-2

Ref. 3D-FS27928

Product Information

• Name: Sulbutiamine
• Synonyms: 2-Methylpropanoic acid 1,1'-[dithiobis[3-[1-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]ethylidene]-3,1-propanediyl]] ester BisibutiamineO-Isobutyroylthiamine disulfide, Arcalion, Arcalion Forte, Bis(1-(2-isobutyryloxyethyl)-2-(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)formamido)-1-propenyl)disulfid, Bis(1-(4-amino-2-methyl-5-pyrimidinyl)-2-formyl-3,9-dimethyl-8-oxo-2-aza-7-oxa-3-decen-4-yl)disulfid, Bisibuthiamine, Bisibutiamin, Bisibutiamine, Brn 0741531, Formamide, N,N'-(dithiobis(2-(2-hydroxyethyl)-1-methylvinylene))bis(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-, diisobutyrate (ester), Isobutyric acid, diester with N,N′-[dithiobis[2-(2-hydroxyethyl)-1-methylvinylene]]bis[N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]formamide], N,N'-(Dithiobis(2-(2-hydroxyethyl)-1-methylvinylene))bis(N-((4-amino-2-methyl-5-pyrimidinyl)methyl)formamide) diisobutyrate (ester), O,O'-Diisobutyrylthiamine disulfide, O-Isobutyroylthiamine disulfide, O-Isobutyrylthiamine disulfide, Propanoic acid, 2-methyl-, 1,1′-[dithiobis[3-[1-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]ethylidene]-3,1-propanediyl]] ester, Propanoic acid, 2-methyl-, dithiobis(3-(1-(((4-amino-2-methyl-5-pyrimidinyl)methyl)formylamino)ethylidene)-3,1-propanediyl) ester, Sulbutiamina, Sulbutiamina [INN-Spanish], Sulbutiaminum, Sulbutiaminum [INN-Latin], Thiamine disulfide O,O-diisobutyrate, Unii-42Ncm1Bw43, Vitaberin, disulfanediylbis(2E)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}pent-2-ene-3,5-diyl bis(2-methylpropanoate)

Description

Sulbutiamine is a thiamine analogue that is used to treat diseases such as Alzheimer's disease and Parkinson's disease. Sulbutiamine also has antimicrobial properties and can be used to treat infectious diseases such as infectious diarrhea. Sulbutiamine has been shown to reduce symptoms of inflammatory bowel disease (IBD) by relieving intestinal inflammation, although it does not affect the course of the disease. Sulbutiamine has also been shown to have effects on the immune system, which may be due to its ability to increase cellular redox potentials in neuro2a cells and human serum. These effects are caused by an indirect antioxidant effect, which results from sulbutiamine's ability to inhibit lipid peroxidation and stimulate glutathione reductase activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 702.89 g/mol
• Formula: C₃₂H₄₆N₈O₆S₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C32H46N8O6S2/c1-19(2)31(43)45-11-9-27(21(5)39(17-41)15-25-13-35-23(7)37-29(25)33)47-48-28(10-12-46-32(44)20(3)4)22(6)40(18-42)16-26-14-36-24(8)38-30(26)34/h13-14,17-20H,9-12,15-16H2,1-8H3,(H2,33,35,37)(H2,34,36,38)/b27-21-,28-22-
• InChI key: InChIKey=CKHJPWQVLKHBIH-ZDSKVHJSSA-N
• SMILES: C/C(=C(\CCOC(=O)C(C)C)SS/C(CCOC(=O)C(C)C)=C(/C)N(C=O)Cc1cnc(C)nc1N)N(C=O)Cc1cnc(C)nc1N