Sincalide

CAS: 25126-32-3

Ref. 3D-FS41124

Product Information

• Name: Sincalide
• Synonyms: (tyr(so3H)27)-cholecystokinin fragment*26-33 amid, Cholecystokinin Octapeptide, Tyr(SO3H]27)Cholecystokinin fragment 26-33 Amide, alpha-aspartyl-O-sulfotyrosylmethionylglycyltryptophylmethionyl-alpha-aspartylphenylalaninamide, L-alpha-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide, Sincalide(CCK-8), Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2, Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-5-L-methionine-, Cholecystokinin C-terminal octapeptide, Cholecystokinin octapeptide (26-33 sulfated), Cholecystokinin-(26-33)-amide, Cholecystokinin-8 (chicken), Cholecystokinin-8 (pig), Cholecystokinin-8 (Squalus acanthias), Cholecystokinin-8 (swine), Cholecystokinin-pancreozymin (swine intestine C-terminal octapeptide), Cholecystokinin-pancreozymin C-terminal octapeptide, Human CCK-8, L-Phenylalaninamide, L-α-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-, Sincalid, Sincalida, Sq 19844
• CAS: 25126-32-3

Description

Sincalide is a cholecystokinin (CCK) analog that has been used as a pharmacological agent. It is an agonist for CCK-A receptors and inhibits the activity of protein kinase C. Sincalide also has been shown to suppress tumor growth in experimental models. A polymerase chain reaction analysis of cck-8, a rat CCK receptor gene, showed a high degree of homology with human CCK-A receptor genes. The physiological effects of sincalide are complex and depend on the presence or absence of other hormones such as insulin, glucagon, somatostatin, and leptin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,143.27 g/mol
• Formula: C₄₉H₆₂N₁₀O₁₆S₃
• Purity: Min. 95%
• Color/Form: Powder