Succinyl-L-proline

CAS: 63250-32-8

Ref. 3D-FS49385

Product Information

• Name: Succinyl-L-proline
• Synonyms: Suc-L-Pro-OH, (2S)-1-(3-Carboxypropanoyl)pyrrolidine-2-carboxylic acid, (2S)-2-Carboxy-γ-oxo-1-pyrrolidinebutanoic acid, 1-(3-carboxypropanoyl)-L-proline, 1-Pyrrolidinebutanoic acid, 2-carboxy-gamma-oxo-, (S)-, 1-Pyrrolidinebutanoic acid, 2-carboxy-γ-oxo-, (2S)-, 1-Pyrrolidinebutanoic acid, 2-carboxy-γ-oxo-, (S)-, Sq 13745, Suc-Pro-OH, Succinylproline

Description

Succinyl-L-proline is a synthetic substrate for carboxypeptidase and other enzymes that catalyzes the hydrolysis of ester bonds. It is a bioactive molecule that has been shown to promote the growth of haematopoietic stem cells in vitro. Succinyl-L-proline has also been shown to lower blood pressure, although it does not have significant effects on serum creatinine levels. The high specificity of succinyl-L-proline makes it a useful substrate for determining the activity of carboxypeptidases, such as carboxypeptidase A and B. Succinyl-L-proline is an isomer of captopril (a drug used to treat hypertension), but it does not cause the side effects associated with captopril, such as myopathy or hyperkalemia.

• Brand: Biosynth

Chemical properties

• Molecular weight: 215.2 g/mol
• Formula: C₉H₁₃NO₅
• Purity: Min. 95%
• InChI: InChI=1S/C9H13NO5/c11-7(3-4-8(12)13)10-5-1-2-6(10)9(14)15/h6H,1-5H2,(H,12,13)(H,14,15)/t6-/m0/s1
• InChI key: InChIKey=NEBOPDYAXPDYHQ-LURJTMIESA-N
• SMILES: O=C(O)CCC(=O)N1CCC[C@H]1C(=O)O