Spinosin

CAS: 72063-39-9

Ref. 3D-FS65586

Product Information

• Name: Spinosin
• Synonyms: Spinocin
• Brand: Biosynth
• Description: Spinosin is a natural product that belongs to the group of pyrrolizidine alkaloids. It has been shown to have physiological function as it can inhibit the 5-HT1A receptor and thereby regulate neurotransmitter release. Spinosin also has anti-inflammatory effects and can be used in the treatment of skin disorders, such as psoriasis. In vitro studies have shown that spinosin is a substrate for P-gp and interacts with other drugs by inhibiting their absorption in the gut and liver. Spinosin has been found to bind to monoclonal antibodies, which may be due to its structural similarity to chinese herb, a known antigenic protein. This leads to increased uptake of spinosin into cells and thus makes it an analytical method for measuring spinosin in biological samples. Spinosin activates p38mapk which then causes the phosphorylation of ERK1/2, leading to receptor binding and activation of downstream signaling pathways.

Chemical properties

• Molecular weight: 608.54 g/mol
• Formula: C₂₈H₃₂O₁₅
• Purity: Min. 95%
• Color/Form: Powder