Shikonin

CAS: 517-89-5

Ref. 3D-FS65933

Product Information

• Name: Shikonin
• Synonyms: (R)-(+)-Shikonin, 1,4-Naphthalenedione 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-, 1,4-Naphthalenedione, 5,8-Dihydroxy-2-(1-Hydroxy-4-Methyl-3-Penten-1-Yl)-, 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-, 1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-, 1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (+)-, 5,8-Dihydroxy-2-(1-Hydroxy-4-Methylpent-3-En-1-Yl)Naphthalene-1,4-Dione, 5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)-1,4-naphthoquinone, 5,8-Dihydroxy-2-[(1R)-1-Hydroxy-4-Methyl-Pent-3-Enyl]Naphthalene-1,4-Dione, 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]naphthalene-1,4-dione, Isoarnebin 4, NSC 252844, Shikonin S, Shikonine, Tokyo Violet

Description

Shikonin is a natural product from the roots of Lithospermum erythroryzon, used in the Chinese herbal medicine under the name Zicao. Shikonin has a broad spectrum of pharmacological activities with antioxidant, anti-inflammatory, antimicrobial, antithrombotic and anti-tumoral properties. Shikonin also has the ability to inhibit the main protease Mpro from coronaviruses, and inhibit the Mpro protease from SARS-CoV-2 with an IC50 of 15.75 μM.

• Brand: Biosynth

Chemical properties

• Molecular weight: 288.3 g/mol
• Formula: C₁₆H₁₆O₅
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1
• InChI key: InChIKey=NEZONWMXZKDMKF-SNVBAGLBSA-N
• SMILES: CC(C)=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O