Product Information
Name:Saligenin
Synonyms:
- O-Hydroxybenzyl alcoholSalicyl alcohol
Brand:Biosynth
Description:Saligenin is a pro-apoptotic protein that belongs to the group of sesquiterpene lactones. It has been shown to induce apoptosis in a model system and in cells grown in vitro. Saligenin induces apoptosis by inhibiting protein synthesis and by inducing reactive oxygen species (ROS) production. This protein also has an inhibitory effect on the phosphorylation of Akt, which is involved in the regulation of cell survival, proliferation, and differentiation. Saligenin has been shown to induce apoptosis in human serum erythrocytes when used at sublethal doses. The mechanism of saligenin-mediated apoptosis involves cleavage of caspase 3 by a protease called calpain. Saligenin also binds to human serum albumin (HSA), which may be related to its plasma stability and intracellular localization.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:124.14 g/mol
Formula:C7H8O2
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2
InChI key:InChIKey=CQRYARSYNCAZFO-UHFFFAOYSA-N
SMILES:OCc1ccccc1O
Technical inquiry about: Saligenin
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