Product Information
Name:(2Z)-Afatinib
Brand:Biosynth
Description:Afatinib is a potent, selective, and ATP-competitive inhibitor of EGFR. It blocks the phosphorylation of tyrosine residues on the extracellular domain of EGFR, thereby inhibiting receptor activation and causing inhibition of tumor cell proliferation in vitro and in vivo. Afatinib has been used as a research tool to study the function and regulation of EGFR signaling pathways. Afatinib has also been shown to block activation of the human transient receptor potential channel TRPM8 by menthol, which may be due to its ability to inhibit protein interactions with the channel.
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Chemical properties
Molecular weight:485.9 g/mol
Formula:C24H25ClFN5O3
Purity:Min. 95%
Technical inquiry about: (2Z)-Afatinib
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