Product Information
Name:JZP 361
Brand:Biosynth
Description:JZP 361 is a peptide fragment of the human protein, thrombospondin-1. It is a potent inhibitor of TGF-β1 and IL-1β signaling, which are both implicated in inflammatory responses. JZP 361 has been shown to inhibit IL-6 production by macrophages and to activate neutrophils by increasing the expression of CD11b and CD18 proteins. These effects may be mediated through interactions with TGF-β receptors, IL-1 receptors, or integrins. The antibody against JZP 361 has been shown to bind specifically to the peptide fragment at pH 7.4 in a range of 1–500 nM concentration.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:405.9 g/mol
Formula:C22H20ClN5O
Purity:Min. 95%
Technical inquiry about: JZP 361
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