Product Information
- 1,1,2-Trifluoroethanol
- 2,2,2-Trifluoraethanol
- 2,2,2-Trifluorethanol
- 2,2,2-Trifluoroetanol
- 2,2,2-Trifluoroethan-1-ol
- 2,2,2-Trifluoroethyl alcohol
- Chloro(Difluoro)Acetic Acid
- Ethanol, 2,2,2-trifluoro-
- Nsc 451
- TFE
- See more synonyms
- Trifluoroethanol
- Trifluroroethyl alchohol
- β,β,β-Trifluoroethyl alcohol
2,2,2-Trifluoroethanol is a trifluoroacetic acid analogue that has been shown to be an effective antimicrobial agent. It binds to the active site of the enzyme enoyl reductase, inhibiting the synthesis of fatty acids and disrupting cell membrane function. 2,2,2-Trifluoroethanol has also been shown to have anti-inflammatory effects. The drug binds to human serum albumin and inhibits hydrogen peroxide release from neutrophils. This complexation with albumin prevents the release of hydroxyl radicals that are generated in response to oxidative stress. Intramolecular hydrogen bonding between 2,2,2-trifluoroethanol molecules may also contribute to its activity as a natural drug.
Chemical properties
Technical inquiry about: 3D-FT00267 2,2,2-Trifluoroethanol
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