Tetrabromo-1,4-benzoquinone

CAS: 488-48-2

Ref. 3D-FT03101

Product Information

• Name: Tetrabromo-1,4-benzoquinone
• Synonyms: p-Bromanil, 2,3,5,6-Tetrabromo-1,4-benzoquinone, 2,3,5,6-Tetrabromo-2,5-cyclohexadiene-1,4-dione, 2,3,5,6-Tetrabromo-p-benzoquinone, 2,3,5,6-Tetrabromocyclohexa-2,5-Diene-1,4-Dione, 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrabromo-, 3,4,5,6-Tetrabromocyclohexadiene-1,2-dione, Bromanil, Bromanyl, Nsc 36927, Quinone, tetrabromo-, Tetrabromo-p-quinone, Tetrabromobenzoquinone, Tetrabromoquinone, p-Benzoquinone, 2,3,5,6-tetrabromo-, p-Benzoquinone, tetrabromo-, p-Bromoanil, p-Quinone, tetrabromo-

Description

Tetrabromo-1,4-benzoquinone is a synthetic reagent that inhibits the activity of dopamine β-hydroxylase, an enzyme involved in the synthesis of norepinephrine. Tetrabromo-1,4-benzoquinone has been shown to inhibit the oxidation of propranolol hydrochloride by hydrochloric acid and its transfer reactions with dopamine. The optimum concentration for this inhibitor is 8 mM. This reaction mechanism is similar to that of catecholamines such as dopamine and norepinephrine. The kinetic data shows that tetrabromo-1,4-benzoquinone has inhibitory properties on the enzyme's activity at concentrations greater than or equal to 2 mM.

• Brand: Biosynth

Chemical properties

• Molecular weight: 423.68 g/mol
• Formula: C₆Br₄O₂
• Purity: Min. 95%
• InChI: InChI=1S/C6Br4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11
• InChI key: InChIKey=LWHDQPLUIFIFFT-UHFFFAOYSA-N
• SMILES: O=C1C(Br)=C(Br)C(=O)C(Br)=C1Br