TBTU

CAS: 125700-67-6

Ref. 3D-FT07096

Product Information

• Name: TBTU
• Synonyms: N,N,N',N'-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborateO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluorob orate, (Benzotriazol-1-yloxy-dimethylamino-methylene)dimethylammonium tetrafluoroborate, 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-), 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1), 2-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyluronium Tetrafluoroborate, 2-(1H-Benzotriazol-1-yl)-N,N,N′,N′-tetramethylammonium tetrafluoroborate, Benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate, Knorr Reagent, N,N,N',N'-tetramethyl-O-(Benzotriazol-1-YL)uronium Tetrafluoroborate, N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium Tetrafluoroborate, O-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyl-uronium Tetrafluoroborate, O-(1H-Benzotriazol-1-YL)-N,N,N',N'-tetramethyluronium Tetrafluoroborate, O-(1H-Benzotriazole-1-YL) N,N,N',N'-tetramethyl uronium Tetrafluoroborate, O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium Tetrafluoroborate, O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, O-(Benzotriazol-l-yl)-N,N,N,N,-tetramethyluronium Tetrafluoroborate, O-Benzotriazol-1-yl-tetramethyluronium tetrafluoroborate, O-Benzotriazolyl tetramethylisouronium tetrafluoroborate, Tbtu

Description

TBTU is an aminium coupling reagent used for amide and ester synthesis. TBTU is a stable, efficient and reactive reagent suitable for solution and solid-phase peptide synthesis. With TBTU high yields, racemisation suppression and fast reaction times are achieved. TBTU contains the carbodiimide and benzotriazole moieties, generates HOBt and water-soluble by-products. TBTU can be used in its polymer-bound form as a solid-supported peptide coupling reagent efficient even in presence of water and can be easily separated and regenerated after the reaction. TBTU finds application in the synthesis of biologically active peptides, such as azapeptides.

• Brand: Biosynth

Chemical properties

• Molecular weight: 321.08 g/mol
• Formula: C₁₁H₁₆N₅O·BF₄
• Purity: Min. 99 Area-%
• Color/Form: White Off-White Powder