2-Thioxanthine

CAS: 2487-40-3

Ref. 3D-FT08196

Product Information

• Name: 2-Thioxanthine
• Synonyms: 2-Mercapto-6-hydroxypurine6-Hydroxy-2-mercaptopurine, 1,2,3,9-Tetrahydro-2-thioxo-6H-purin-6-one, 2,3-Dihydro-2-thioxo-9H-purin-6(1H)-one, 2-Mecapto-6-hydroxypurine, 2-Mercapto-1,9-dihydro-purin-6-one, 2-Mercapto-6-hydroxypurine, 2-Mercaptohypoxanthine, 2-Sulfanyl-1H-purin-6-ol, 2-Sulfanyl-6,7-dihydro-1H-purin-6-one, 2-Sulfanyl-6,9-dihydro-1H-purin-6-one, 2-Sulfanyl-7H-purin-6-ol, 2-Sulfanylidene-2,3,6,7-tetrahydro-1H-purin-6-one, 2-Sulfanylidene-3,7-dihydropurin-6-one, 2-Thio-6-hydroxypurine, 2-Thioxo-2,3-dihydro-1H-purin-6(7H)-one, 2-thioxo-1,2,3,5-tetrahydro-6H-purin-6-one, 2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one, 6-Hydroxy-2-mercaptopurine, 6-Hydroxypurine-2-thiol, 6H-Purin-6-one, 1,2,3,7-tetrahydro-2-thioxo-, 6H-Purin-6-one, 1,2,3,9-tetrahydro-2-thioxo-, NSC 36822, NSC 680828, Xanthine, 2-thio-

Description

2-Thioxanthine is a hydrated form of xanthine, which is a purine base that occurs in all living cells. This compound has been shown to be able to inhibit the growth of resistant mutants and the formation of atherosclerotic lesions in mice. 2-Thioxanthine also inhibits the transfer reactions that are required for bacterial DNA synthesis. The stability of 2-thioxanthine can be increased by forming stable complexes with hydrochloric acid and by reducing the pH to less than 7. 2-Thioxanthine has been shown to have genotoxic effects on mouse liver cells and human fibroblasts, as well as pharmacological properties against cardiovascular disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 168.18 g/mol
• Formula: C₅H₄N₄OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H4N4OS/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
• InChI key: InChIKey=XNHFAGRBSMMFKL-UHFFFAOYSA-N
• SMILES: O=c1[nH]c(=S)[nH]c2nc[nH]c12