Tanshinone I

CAS: 568-73-0

Ref. 3D-FT09979

Product Information

• Name: Tanshinone I
• Synonyms: 1,6-Dimethyl-phenanthro[1,2-b]furan-10,11-dione, 1,6-Dimethylphenanthro[1,2-b]furan-10,11-dione, Phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl-, Tanshinon I, Tanshinone A

Description

Tanshinone I is a natural compound that has been shown to have antibacterial efficacy against methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. Tanshinone I also has pro-apoptotic effects in cancer cells and increased neuronal death in brain cells. It is also used as an anti-inflammatory agent, inhibiting the activity of MMP-9, which breaks down collagen. This inhibition leads to the reduction of atherosclerotic lesions and the prevention of myocardial infarcts. Tanshinone I binds to dinucleotide phosphate (DNP) in the DNA sequence, preventing DNA from uncoiling or replicating properly. This inhibits cell growth by binding to dNTPs and blocking DNA synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 276.29 g/mol
• Formula: C₁₈H₁₂O₃
• Purity: Min. 95%
• Color/Form: Red Powder
• InChI: InChI=1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3
• InChI key: InChIKey=AIGAZQPHXLWMOJ-UHFFFAOYSA-N
• SMILES: Cc1coc2c1C(=O)C(=O)c1c-2ccc2c(C)cccc12