Thiophene-2-carbaldehyde oxime

Ref. 3D-FT123022

Product Information

• Name: Thiophene-2-carbaldehyde oxime
• Synonyms: 2-thiophenecarboxaldehyde, oxime
• Brand: Biosynth
• Description: Thiophene-2-carbaldehyde oxime is a reaction product of 2-aminoethanethiol and thiophene-2-carbaldehyde. It has a high antibacterial activity against Pseudomonas aeruginosa, which is the most common cause of hospital-acquired infections. Thiophene-2-carbaldehyde oxime has been shown to react with metal ions to form an insoluble precipitate in aqueous solution, which may be responsible for its antibacterial activity. It also inhibits acetylcholinesterase (AChE) by forming an adduct with the enzyme's active site. The inhibition of AChE results in increased levels of acetylcholine, leading to increased muscle contractions and paralysis.

Chemical properties

• Molecular weight: 127.17 g/mol
• Formula: C₅H₅NOS
• Purity: Min. 95%
• InChI: InChI=1S/C5H5NOS/c7-6-4-5-2-1-3-8-5/h1-4,7H/b6-4+
• InChI key: InChIKey=GASLBPLHYRZLLT-GQCTYLIASA-N
• SMILES: O/N=C/c1cccs1