2-(Trifluoromethoxy)benzoic acid

CAS: 1979-29-9

Ref. 3D-FT13238

Product Information

• Name: 2-(Trifluoromethoxy)benzoic acid
• Synonyms: 2-(Trifluoromethoxy)Benzoate, O-Trifluoromethoxybenzoic Acid

Description

2-(Trifluoromethoxy)benzoic acid is a polycarboxylic acid that has been used in clinical studies to treat congestive heart failure. It activates the hydroxyl group of 2-substituted benzoic acids, leading to their site-specific reactions with nucleophiles. These reactions are useful in the study of DNA and RNA synthesis, as well as protein synthesis. 2-(Trifluoromethoxy)benzoic acid has also been shown to be effective against basophilic leukemias and is considered to be a carbonic anhydrase inhibitor.
2-(Trifluoromethoxy)benzoic acid inhibits the enzyme carbonic anhydrase, which catalyzes the conversion of CO2 into HCO3-. This inhibition leads to increased levels of bicarbonate ions in the blood, which can result in a decrease in blood pH levels (acidosis). The acidic environment may cause

• Brand: Biosynth

Chemical properties

• Molecular weight: 206.12 g/mol
• Formula: C₈H₅F₃O₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H5F3O3/c9-8(10,11)14-6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)
• InChI key: InChIKey=JMYSPFGUBNENSE-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccccc1OC(F)(F)F