Product Information
- A mixture in the ratio 2:1 of two polypeptides, thaumatin I and II, each consisting of 207 amino acid residues and having a molecular weight of about 22,000, extracted from the aril of the tropical fruit Thaumatococcus daniellii
- FEMA No. 3732
- Hsdb 3927
- Ketemfe fruit extract
- Neo San Maruku AG
- Neo San Maruku DC
- Plant proteins, talin
- Proteins, specific or class, thaumatins
- Sansweet T
- Sansweet T 147
- See more synonyms
- Sweeteners, talin
- Talin
- Talin (flavor protein)
- Talin (plant protein)
- Talin sweetener
- Thaumatin II
- Thaumatin [BAN]
- Thaumatins
- Thaumatins, thaumatin II
- Proteins, thaumatins
Thaumatin is a natural sweetener that is extracted from the katemfe fruit. It shares structural similarities with basic proteins and has been shown to inhibit enzyme activity in vitro. Thaumatin has also been shown to inhibit transcription-polymerase chain reaction (PCR) and protein synthesis in vitro, which may be due to its ability to bind to DNA and RNA. This binding inhibits ribosomal protein (rp) function, leading to the inhibition of mRNA translation. The carboxy terminal sequence of thaumatin is essential for its biological activity, as deletion of this region abolishes enzyme inhibition. Structural analysis has revealed that thaumatin interacts with RNA by forming hydrogen bonds with nucleotides in the major groove and stacking interactions with nucleotides in the minor groove. X-ray diffraction data has confirmed these findings, revealing that thaumatin binds to DNA at specific sites on the sugar-phosphate backbone.
Chemical properties
Technical inquiry about: 3D-FT139142 Thaumatin
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