2,4,6-Trichloro-5-nitropyrimidine

CAS: 4359-87-9

Ref. 3D-FT154562

Product Information

• Name: 2,4,6-Trichloro-5-nitropyrimidine
• Brand: Biosynth

Description

2,4,6-Trichloro-5-nitropyrimidine is a purine derivative that inhibits the cell proliferation of cancer cells. It has been shown to inhibit the activity of kinases and to induce apoptosis in human cancer cells in vitro. This drug also has antiproliferative potential against erythrocytes and is being investigated as a treatment for renal disease. 2,4,6-Trichloro-5-nitropyrimidine shows inhibitory effects on the phosphorylation of roscovitine by ATP and may be used to treat patients with glomerulonephritis. 2,4,6-Trichloro-5-nitropyrimidine can be synthesized from 2,4,6-trichloropyrimidinethiol and nitric acid according to the following equation: CClNO + HNO → CClNOH + NO 2 Cl + 3 HNO

Chemical properties

• Molecular weight: 228.42 g/mol
• Formula: C₄Cl₃N₃O₂
• Purity: Min. 97 Area-%