Trichlorfon

CAS: 52-68-6

Ref. 3D-FT159085

Product Information

• Name: Trichlorfon
• Synonyms: Metrifonate(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester
• Brand: Biosynth
• Description: Trichlorfon is a surfactant sodium dodecyl that is used as a pharmacological agent. It is an organophosphate insecticide that inhibits the enzyme cholinesterase and acts as an acetylcholinesterase inhibitor. Trichlorfon has also been shown to inhibit the activity of GSH-px, which is important in the metabolism of xenobiotics and oxidative stress. Trichlorfon has been used in treatment trials for infectious diseases such as malaria. The drug has been shown to have acute toxicities, such as seizures, coma, and respiratory arrest. These side effects are primarily due to its effects on central nervous system functions, including inhibition of acetylcholine receptors and muscarinic receptors, which are involved in basic physiological processes like muscle control and breathing. This drug also affects complex enzymes such as protein synthesis and DNA synthesis.

Chemical properties

• Molecular weight: 257.44 g/mol
• Formula: C₄H₈Cl₃O₄P
• Purity: Min. 95%
• InChI: InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
• InChI key: InChIKey=NFACJZMKEDPNKN-UHFFFAOYSA-N
• SMILES: COP(=O)(OC)C(O)C(Cl)(Cl)Cl