Thiazolidine-2,4-dione

CAS: 2295-31-0

Ref. 3D-FT16406

Product Information

• Name: Thiazolidine-2,4-dione
• Synonyms: 1,3-Thiazolidine-2,4-dione2,4-Thiazolidinedione, 1,3-Thiazolidine-2,4-Dione, 2,4(3H,5H)-Thiazoledione, 2,4-Dioxo-1,3-thiazolidine, 2,4-Dioxothiazolidine, 2,4-Thiadolidinedione, 2-Hydroxy-4,5-dihydro-1,3-thiazol-4-one, 2-Thiazolin-4-one, 2-hydroxy-, Nsc 6745, Otava-Bb Bb7112440002, TZD, Thiazole-2,4-dione, Thiazolidin-2,4-dion, Thiazolidin-2,4-dione, Thiazolidinedione, Thiazolidinedione-2,4, Tiazolidina-2,4-Diona, Timtec-Bb Sbb000047, U 25560

Description

Thiazolidine-2,4-dione (THZ) is a drug that has been shown to be an orally active, anti-inflammatory agent with postprandial blood glucose lowering properties. It inhibits the nuclear factor kappa B (NF-κB) binding activity and suppresses inflammation in vitro and in vivo. THZ also has hypoglycemic effects and may be used as an oral hypoglycemic agent for the treatment of diabetes mellitus type 2. THZ is not active against bowel disease or atherosclerosis. It interacts with other drugs, such as statins, which reduce its hypoglycemic effects. This drug also intercalates into DNA and binds to response elements related to inflammation and insulin signalling pathways.

• Brand: Biosynth

Chemical properties

• Molecular weight: 117.13 g/mol
• Formula: C₃H₃NO₂S
• Purity: Min. 89.0%
• Color/Form: Powder
• InChI: InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
• InChI key: InChIKey=ZOBPZXTWZATXDG-UHFFFAOYSA-N
• SMILES: O=C1CSC(=O)N1