Trans-4,5-Epoxy-2(E)-Decenal

CAS: 134454-31-2

Ref. 3D-FT171968

Product Information

• Name: Trans-4,5-Epoxy-2(E)-Decenal
• Synonyms: 2-Propenal, 3-(3-pentyloxiranyl)-, [2α(E),3β]-, 2-Propenal, 3-[(2R,3R)-3-pentyl-2-oxiranyl]-, (2E)-rel-, 2-Propenal, 3-[(2R,3R)-3-pentyloxiranyl]-, (2E)-rel-, 3-[(2R,3R)-3-Pentyloxiranyl]-2E-Propenal, 4,5-Epoxy-(E)-2-Decenal, 4,5-Epoxy-(E)-dec-2-enal, Fema 4037, epoxy-2-decenal,(E)-4,5-epoxy-(E)-2-decenal, rel-(2E)-3-[(2R,3R)-3-Pentyl-2-oxiranyl]-2-propenal, trans-4,5-Epoxy-(E)-2-decenal

Description

Trans-4,5-Epoxy-2(E)-Decenal is a polyunsaturated molecule that can react with amines to form nitrosamines. This compound is found in fried foods and has been shown to inhibit the activity of detoxification enzymes. Trans-4,5-Epoxy-2(E)-Decenal reacts with reactive oxygen species and forms DNA adducts, which are mutagenic and carcinogenic. It also is able to induce the production of malondialdehyde, a marker for lipid peroxidation. The effect of this compound on cancer cells was assessed using CD1 mouse skin cells in vitro and in vivo. In vitro studies showed that trans-4,5-epoxy-2(E)-decenal inhibited transcriptional regulation by downregulating fatty acid synthase expression and upregulating p21 protein expression. In vivo studies demonstrated that trans-4,5-epoxy-2(E)-decenal

• Brand: Biosynth

Chemical properties

• Molecular weight: 168.23 g/mol
• Formula: C₁₀H₁₆O₂
• Purity: Min. 95%