Product Information
TPX0131 is a recombinant human anti-IL8 antibody. TPX0131 has been shown to inhibit IL8 induced neutrophil chemotaxis and to block the IL8 receptor. TPX0131 also blocks the activation of NF-κB, a transcription factor involved in inflammation, and inhibits IL8 induced expression of adhesion molecules on endothelial cells. The affinity of TPX0131 for IL8 is low (Kd=1.5 nM) and it has high purity (>98%).
Chemical properties
Technical inquiry about: 3D-FT181395 TPX0131
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