TPX0131

CAS: 2648641-36-3

Ref. 3D-FT181395

Product Information

• Name: TPX0131
• Brand: Biosynth
• Description: TPX0131 is a recombinant human anti-IL8 antibody. TPX0131 has been shown to inhibit IL8 induced neutrophil chemotaxis and to block the IL8 receptor. TPX0131 also blocks the activation of NF-κB, a transcription factor involved in inflammation, and inhibits IL8 induced expression of adhesion molecules on endothelial cells. The affinity of TPX0131 for IL8 is low (Kd=1.5 nM) and it has high purity (>98%).

Chemical properties

• Molecular weight: 447.4 g/mol
• Formula: C₂₁H₂₀F₃N₅O₃
• Purity: Min. 95%