4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride

CAS: 2413-38-9

Ref. 3D-FT23498

Product Information

• Name: 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
• Synonyms: (Z/E)-Fupentixol dihydrochloride, (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol dihydrochloride, 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, dihydrochloride, 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2), 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]-, dihydrochloride, 2-(4-{(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol, 2-(4-{(3Z)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride, 2-(4-{3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride, 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol dihydrochloride, Emergil, Flupentixol Hydrochloride, Flupentixol dihydrochloride, Fx 703, Metamin, Siplarol

Description

4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride is a potent antagonist of the 5-HT2A receptor. It has been shown to reduce body weight and food intake in animal models. The compound has also been shown to decrease motor activity and increase grooming behavior, which are symptoms of Parkinson's disease. 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride is a Pgp substrate and can be used to measure the activity of this transporter in human serum, as well as determining its effect on renal function in rats.

• Brand: Biosynth

Chemical properties

• Molecular weight: 507.44 g/mol
• Formula: C₂₃H₂₇Cl₂F₃N₂OS
• Purity: Min. 95%
• Color/Form: Powder