Tamoxifen N-oxide
CAS:
Ref. 3D-FT27997
2mg
262.00€
5mg
341.00€
10mg
547.00€
25mg
1,085.00€
50mg
1,627.00€
Product Information
Name:Tamoxifen N-oxide
Synonyms:
- (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine N-oxide
Brand:Biosynth
Description:Tamoxifen N-oxide is a prodrug of tamoxifen, which is a drug used for the treatment and prevention of breast cancer. Tamoxifen N-oxide has been shown to have genotoxic effects in human liver cells. The deuterium isotope effect on the metabolism of tamoxifen N-oxide was studied using unlabelled and labelled substrates. The results showed that it is metabolized by cytochrome P450 enzymes, mainly CYP3A4. The optimum pH for activity of this enzyme is 7.8 while the optimum pH for activity of CYP2D6 is 8.5.
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Chemical properties
Molecular weight:387.51 g/mol
Formula:C26H29NO2
Purity:Min. 95%
Color/Form:White Powder
Technical inquiry about: Tamoxifen N-oxide
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