(S)-(-)-Thalidomide

CAS: 841-67-8

Ref. 3D-FT28191

Product Information

• Name: (S)-(-)-Thalidomide
• Synonyms: (S)-(-)-2-(2,6-Dioxo-3-piperidinyl)-1H-iso-indole-1,3(2H)-dione(S)-ThalidomideNSC 91730, (-)-Thalidomide, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (S)-, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (S)- (9CI), 1H-isoindole-1,3(2H)-dione, 2-[(3S)-2,6-dioxo-3-piperidinyl]-, 2-[(3S)-2,6-Dioxo-3-piperidinyl]-1H-isoindole-1,3(2H)-dione, 2-[(3S)-2,6-Dioxopiperidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione, 841-67-8, NSC 91730, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, <span class="text-smallcaps">L</span>-(-)-, S-(-)-Thalidomide, S-(<span class="text-smallcaps">L</span>)-Thalidomide, S-Lenalidomide, T56 BVNVJ C- DT6VMVTJ & & (S)-(-)- Form, Thalidomide, L-, Phthalimide, N-(2,6-dioxo-3-piperidyl)-, L-(-)-

Description

Thalidomide is a drug that is used to treat human immunodeficiency, but has been found to have some side effects. It is an immunomodulatory drug that alters the immune system by suppressing the production of cytokines such as TNF-α and IL-1β. Thalidomide inhibits the production of prostaglandins, which are inflammatory mediators. It also has been shown to be effective in treating erythema nodosum leprosum and Behçet's disease. The molecular structure of thalidomide contains two chiral centers: carbonyl group and chlorine. The (S) form is more active than its enantiomer (R). Thalidomide can cause serious adverse reactions, including peripheral neuropathy, constipation, hiccoughs, tachycardia, insomnia, dizziness, nausea and vomiting.

• Brand: Biosynth

Chemical properties

• Molecular weight: 258.23 g/mol
• Formula: C₁₃H₁₀N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)/t9-/m0/s1
• InChI key: InChIKey=UEJJHQNACJXSKW-VIFPVBQESA-N
• SMILES: O=C1CC[C@H](N2C(=O)c3ccccc3C2=O)C(=O)N1