L-threo-methylphenidate hydrochloride

CAS: 40572-71-2

Ref. 3D-FT28256

Product Information

• Name: L-threo-methylphenidate hydrochloride
• Synonyms: (2S,2'S)-(-)-threo-methyl a-phenyl-a-(2-piperidyl)acetate hydrochloride
• Brand: Biosynth
• Description: L-threo-methylphenidate hydrochloride is a drug with a long duration of action. It has been shown to be effective in the treatment of ADHD symptoms and is used as an alternative to dexmethylphenidate. L-threo-methylphenidate hydrochloride is metabolized by cytochrome P450s, which results in slower pharmacokinetics, but also increases its bioavailability. L-threo-methylphenidate hydrochloride inhibits the activity of dopamine transporters, which leads to increased extracellular dopamine levels and reduced locomotor activity in mice. This drug has been shown to have an anti-inflammatory effect on alopecia areata and may be useful as a treatment for this condition. L-threo-methylphenidate hydrochloride has also been shown to have a protective effect against neurotoxicity induced by methamphetamine in CD1 mice.

Chemical properties

• Molecular weight: 269.77 g/mol
• Formula: C₁₄H₂₀ClNO₂
• Purity: Min. 95%