D,L-Threo-b-hydroxy aspartic acid

CAS: 4294-45-5

Ref. 3D-FT28259

Product Information

• Name: D,L-Threo-b-hydroxy aspartic acid
• Synonyms: DL-tHya, threo-2-amino-3-hydroxysuccinic acid, (3R)-2-amino-3-hydroxy-butanedioic acid, <span class="text-smallcaps">D</span>-Aspartic acid, 3-hydroxy-, (3R)-rel-, <span class="text-smallcaps">DL</span>-Aspartic acid, 3-hydroxy-, threo-, <span class="text-smallcaps">DL</span>-threo-3-Hydroxyaspartic acid, <span class="text-smallcaps">DL</span>-threo-β-Hydroxyaspartic acid, Aspartic acid, 3-hydroxy-, <span class="text-smallcaps">DL</span>-threo-, DL-threo--Hydroxyaspartic Acid, rel-(3R)-3-Hydroxy-<span class="text-smallcaps">D</span>-aspartic acid, threo-3-Hydroxy-<span class="text-smallcaps">DL</span>-aspartic acid

Description

D,L-Threo-b-hydroxy aspartic acid is a stereoselective synthetic amino acid that has been used to study the uptake and hydrolysis of D,L-threo-b-hydroxy aspartic acid by rat brain synaptosomes. It has also been used in the synthesis of an L-alanine analogue with the same stereochemistry at the chiral center. The stereoselective synthesis of this compound is achieved by epimerization reaction using d-alanine as a starting material. Threo bhda has been shown to inhibit glutamate release from neurons and stimulate GABA release in synaptosomes, which may be due to its ability to bind to ion channels. Threo bhda has also been found to inhibit the binding of radioactive thymidine to calf thymus DNA with a high degree of stereoselectivity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.1 g/mol
• Formula: C₄H₇NO₅
• Purity: Min. 95%