Tienilic acid

CAS: 40180-04-9

Ref. 3D-FT28272

Product Information

• Name: Tienilic acid
• Synonyms: [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acidTicrynafenDiflurexANP-3624Selacryn, 2,3-Dichloro-4-(2-thenoyl)phenoxyacetic acid, 2-[2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid, 2-[2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid, 4-(2-Thenoyl)-2,3-dichlorophenoxyacetic acid, 4-(2-Thienylcarbonyl)-2,3-dichlorophenoxyacetic acid, Acetic Acid, 2-[2,3-Dichloro-4-(2-Thienylcarbonyl)Phenoxy]-, Acetic Acid, [2,3-Dichloro-4-(2-Thienylcarbonyl)Phenoxy]-, Anp 3624, Ce 3624, Difluorex, Fr 3068, Selacryn, Skf 62698, Thienylic acid, Ticrynafen, Tienylic acid, [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid, [2,3-Dichloro-4-(Thiophen-2-Ylcarbonyl)Phenoxy]Acetic Acid, {[2,3-Dichloro-4-(2-Thienylcarbonyl)Phenyl]Oxy}Acetic Acid

Description

Tienilic acid is a drug that belongs to the group of diastolic pressure-lowering drugs. It lowers blood pressure by inhibiting the renin-angiotensin system, which is a hormone system that regulates blood pressure. Tienilic acid inhibits the activity of renin and angiotensin converting enzyme (ACE), which are enzymes involved in the production of angiotensin II, a peptide that causes vasoconstriction and stimulates the release of aldosterone from the adrenal gland. Tienilic acid has been shown to be safe for use in humans and animals at doses up to 300 mg/kg/day, although it can cause adverse effects such as drug reactions or drug metabolites. Tienilic acid has also been shown to inhibit protease activity in human liver cells, suggesting that it may have an inhibitory effect on other proteases as well.

• Brand: Biosynth

Chemical properties

• Molecular weight: 331.17 g/mol
• Formula: C₁₃H₈Cl₂O₄S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C13H8Cl2O4S/c14-11-7(13(18)9-2-1-5-20-9)3-4-8(12(11)15)19-6-10(16)17/h1-5H,6H2,(H,16,17)
• InChI key: InChIKey=AGHANLSBXUWXTB-UHFFFAOYSA-N
• SMILES: O=C(O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl