trans-Tranilast

Ref. 3D-FT28370

Product Information

• Name: trans-Tranilast
• Synonyms: 2-[[(2E)-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]benzoic acid(E)-2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzo ic Acid
• Brand: Biosynth
• Description: Trans-Tranilast is a drug that is being investigated for the treatment of inflammatory diseases. It is an experimental drug that has shown potential to reduce atherosclerotic lesions in animal models. Trans-Tranilast inhibits the formation of cell factors, which are compounds that are needed for many cellular processes, including protein synthesis and cell division. In addition, this drug has been shown to inhibit cyclic nucleotide phosphodiesterases and MMP-9 activity in vitro. Trans-Tranilast also prevents balloon injury in mice by reducing the production of growth factor β1 (GF-β1). Trans-Tranilast has a number of mechanisms of action, which may make it an effective treatment for inflammatory diseases.

Chemical properties

• Molecular weight: 327.33 g/mol
• Formula: C₁₈H₁₇NO₅
• Purity: Min. 95%
• InChI: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
• InChI key: InChIKey=NZHGWWWHIYHZNX-CSKARUKUSA-N
• SMILES: COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC