4'-(Trifluoromethyl)acetophenone

CAS: 709-63-7

Ref. 3D-FT28471

Product Information

• Name: 4'-(Trifluoromethyl)acetophenone
• Synonyms: 1-[4-(Trifluoromethyl)phenyl]ethanone(4-Trifluoromethylphenyl) methyl ketone1-(4-Trifluoromethylphenyl)ethanone, (4-Trifluoromethylphenyl) methyl ketone, 1-Acetyl-4-(trifluoromethyl)benzene, 1-[4-(Trifluoromethyl)Phenyl]Ethanone, 1-[4-(Trifluoromethyl)phenyl]-1-ethanone, 2-Bromo-2,2-Difluoroethanamine, 4-Acetylbenzotrifluoride, Acetophenone, 4′-(trifluoromethyl)-, Ethanone, 1-[4-(trifluoromethyl)phenyl]-, Methyl 4-trifluoromethylphenyl ketone, NSC 88346, Sodium4-trifluoromethylbenzoate, p-(Trifluoromethyl)acetophenone, p-Trifluoromethylacetophenone, 4'-(Trifluoromethyl)-Acetophenone, 4'-(Trifluoromethyl)acetophenone, 4[-(Trifluoromethyl)acetophenone, 4-(Trifluoromethyl) acetophenone, 4-(Trifluoromethyl)acetophenone

Description

4'-(Trifluoromethyl)acetophenone is a phosphatase inhibitor that has been shown to have inhibitory activity against chemokines. Chemokines are a type of cytokine that are secreted by immune cells and play an important role in inflammation. 4'-(Trifluoromethyl)acetophenone has also been shown to have an effect on the cell membrane permeability of amines and 2-aminobenzyl alcohol, which are substrates for the enzyme. 4'-(Trifluoromethyl)acetophenone reacts with imidazole derivatives, such as trifluoride, forming hydrogen bonds between the two molecules. Kinetic studies have demonstrated that this reaction is reversible in solution at room temperature.

• Brand: Biosynth

Chemical properties

• Molecular weight: 188.15 g/mol
• Formula: C₉H₇F₃O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C9H7F3O/c1-6(13)7-2-4-8(5-3-7)9(10,11)12/h2-5H,1H3
• InChI key: InChIKey=HHAISVSEJFEWBZ-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccc(C(F)(F)F)cc1