Product Information
Name:Trihydroxycoprostane
Controlled Product
Synonyms:
- (3a,5b,7a,12a)-Cholestane-3,7,12-triol3a,7a,12a-Trihydroxycoprostane
Brand:Biosynth
Description:Trihydroxycoprostane is a natural compound and metabolite of cholesterol. It is produced by the microsomal cytochrome P450 enzymes in the liver, where it is converted to dihydroxycoprostane. Trihydroxycoprostane has been found to be a precursor of acid formation in humans, which may be due to its conversion to p-hydroxyphenylacetaldehyde and then to p-hydroxyphenylacetic acid. The uptake, metabolism and excretion of trihydroxycoprostanes have been studied in human liver cells and rat liver microsomes. This study found that trihydroxycoprostanes are metabolized by 3β-HSD or 3α-HSD and converted into dihydroxycoprostanes. Trihydroxycoprostane has also been shown to increase serum levels of alanine and urea nitrogen, but does not affect cholesterol levels in rats with cerebrotendinous xanthomat
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Chemical properties
Molecular weight:420.67 g/mol
Formula:C27H48O3
Purity:Min. 95%
Technical inquiry about: Trihydroxycoprostane
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