Trisodium phosphonoformate hexahydrate

CAS: 34156-56-4

Ref. 3D-FT28592

Product Information

• Name: Trisodium phosphonoformate hexahydrate
• Synonyms: 1,1-Dihydroxy-phosphinecarboxylic acid 1-oxide sodium salt hydratePhosphono-formic acid trisodium salt hexahydrateFoscarnet sodium hexahydrate, Formic acid, phosphono-, trisodium salt, hexahydrate, Phosphinecarboxylic acid, 1,1-dihydroxy-, 1-oxide, sodium salt, hydrate (1:3:6), Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt, hexahydrate, Phosphoranecarboxylate, 1,1-Dihydroxy-, Oxide, Sodium Salt, Hydrate (1:3:6), Sodium Dioxidophosphanecarboxylate Oxide Hydrate (3:1:6), Sodium phosphonoformate tribasic hexahydrate

Description

Trisodium phosphonoformate hexahydrate is a cytotoxic drug that is used to treat cytomegalovirus infections. It acts by inhibiting viral DNA polymerase and RNA synthesis, leading to cell death. Trisodium phosphonoformate hexahydrate can be used in combination with other antiviral drugs such as ganciclovir or foscarnet sodium for the treatment of HIV-1 infection. Trisodium phosphonoformate hexahydrate can also be used for prophylactic treatment against cytomegalovirus infection in immunosuppressed patients. This drug has been shown to be effective in reducing the incidence of CMV disease and mortality in transplant recipients who were undergoing low-dose chemotherapy. Trisodium phosphonoformate hexahydrate has been shown to be more effective than foscarnet sodium alone in preventing CMV disease and mortality during low-dose chemotherapy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.04 g/mol
• Formula: CH₁₂O₁₁Na₃P
• Purity: Min. 95%
• Color/Form: Powder