Tyrphostin 23

CAS: 118409-57-7

Ref. 3D-FT28633

Product Information

• Name: Tyrphostin 23
• Synonyms: (3,4-Dihydroxybenzylidene)-malononitrile, RG-50810 AG 18, (3,4-Dihydroxybenzylidene)malononitrile, 2-(3,4-Dihydroxybenzylidene)malononitrile, 2-[(3,4-Dihydroxyphenyl)methylene]propanedinitrile, 2-[(3,4-Dihydroxyphenyl)methylidene]propanedinitrile, AG 18 (pharmaceutical), Ag 18, Propanedinitrile, 2-[(3,4-dihydroxyphenyl)methylene]-, Propanedinitrile, [(3,4-dihydroxyphenyl)methylene]-, Rg 50810, Rg 50858, Tx 825, Tyrphostin A 23, Tyrphostin AG 18

Description

Tyrphostin 23 is a chemical inhibitor of protein kinase C (PKC) and PKC-related kinases. It is used to study the role of PKC in cell signaling, as well as its function in various diseases, such as bowel disease. Tyrphostin 23 has been shown to be an activator of basic fibroblast growth factor (bFGF), which may be due to its ability to increase cytosolic calcium levels. It also has been shown to inhibit the polymerase chain reaction (PCR) in a number of cancer cells. Tyrphostin 23 binds to a protein target that is involved in apoptosis pathway and ATP channel activity, inhibiting the ion channels responsible for the flow of cations across the plasma membrane.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.17 g/mol
• Formula: C₁₀H₆N₂O₂
• Purity: Min. 95%
• Color/Form: Powder