p-Toluenesulfonic anhydride

CAS: 4124-41-8

Ref. 3D-FT28875

Product Information

• Name: p-Toluenesulfonic anhydride
• Brand: Biosynth
• Description: p-Toluenesulfonic anhydride is a tosylate reagent for the conversion of alcohols to alkyl tosylates. It is used in chemical biology and biochemistry as a protonation agent, which reacts with nucleophilic groups (e.g., hydroxyl) on proteins or other biomolecules. p-Toluenesulfonic anhydride also has been used in the synthesis of organic compounds, such as drugs, pesticides and herbicides. This compound can be used as a catalyst for palladium-catalyzed coupling reactions that are site specific due to its high reactivity and susceptibility to hydrolysis. p-Toluenesulfonic anhydride is not active on aromatic rings because it does not have a nucleophilic group. This compound can be quantified by gravimetric analysis or FTIR spectroscopy.

Chemical properties

• Molecular weight: 326.39 g/mol
• Formula: C₁₄H₁₄O₅S₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C14H14O5S2/c1-11-3-7-13(8-4-11)20(15,16)19-21(17,18)14-9-5-12(2)6-10-14/h3-10H,1-2H3
• InChI key: InChIKey=PDVFSPNIEOYOQL-UHFFFAOYSA-N
• SMILES: Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccc(C)cc2)cc1