Topotecan

CAS: 123948-87-8

Ref. 3D-FT30185

Product Information

• Name: Topotecan
• Synonyms: (19S)-8-[(Dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione, (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (S)-Topotecan, 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-10-[(dimethylamino)methyl]-, hydrochloride, (S), 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-, 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-, 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin, 9-Dimethylaminomethyl-10-hydroxycamptothecin, HCl salt, Evotopin, Hycamptamine, Hycamptin, NSC 609699, Nogitecan, Potactasol, Skf 104864, Skf-S 104864, TopoCED, Topophore C, Topotecan lactone

Description

Topoisomerase I inhibitor; HIF-1 inhibitor

• Brand: Biosynth

Chemical properties

• Molecular weight: 421.45 g/mol
• Formula: C₂₃H₂₃N₃O₅
• Purity: Min. 95%
• InChI: InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1
• InChI key: InChIKey=UCFGDBYHRUNTLO-QHCPKHFHSA-N
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN(C)C)c(O)ccc3nc2-1