Thieno[3,2-b]pyridin-7-ol

Ref. 3D-FT30401

Product Information

• Name: Thieno[3,2-b]pyridin-7-ol
• Brand: Biosynth
• Description: Thieno[3,2-b]pyridin-7-ol is a methoxylated analog of the nucleoside thymidine. It is programmed to bind to DNA in a sequence specific manner and can be used for the treatment of lung cancer. Thieno[3,2-b]pyridin-7-ol binds to the pBR322 plasmid DNA by an intercalative mechanism. This binding prevents replication and transcription, which leads to cell death. Thieno[3,2-b]pyridin-7-ol has been shown to have a cytotoxic effect on human lung cancer cells in culture. Studies have shown that this drug inhibits tumor growth in mice with breast cancer and rat primary cells with prostate cancer.

Chemical properties

• Molecular weight: 151.19 g/mol
• Formula: C₇H₅NOS
• Purity: Min. 95%