4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-Oxide
CAS: 16352-18-4
Ref. 3D-FT31045
| 1g | To inquire | ||
| 100mg | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- 2-Oxo-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, HASPO-1, Phosphonic acid pinacol ester, Pinacol phosphonate
- 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide is a chiral phosphine oxide that is used as a reagent in organic synthesis. It is often used to make the phosphonate ester 4,4,5,5-tetramethyl-1,3,2-dioxaphospholane 2-oxide by reacting with allyl chloride. 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide is also used as an anionic ligand in coordination chemistry. Mechanistic studies suggest that the elimination of HCl from the dioxaphospholane intermediate occurs via a two step process involving Grignard reagents and phosphines. The first step involves the addition of a Grignard reagent to one of the carbon atoms adjacent to a phosphorus atom in the dioxaphosphol
Chemical properties
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