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4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-Oxide
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4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-Oxide

CAS: 16352-18-4

Ref. 3D-FT31045

1gDiscontinued
100mgDiscontinued
250mgDiscontinued
500mgDiscontinued

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Product Information

Name:
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-Oxide
Synonyms:
  • 2-Oxo-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, HASPO-1, Phosphonic acid pinacol ester, Pinacol phosphonate
  • 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide
Description:

4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide is a chiral phosphine oxide that is used as a reagent in organic synthesis. It is often used to make the phosphonate ester 4,4,5,5-tetramethyl-1,3,2-dioxaphospholane 2-oxide by reacting with allyl chloride. 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholane 2-oxide is also used as an anionic ligand in coordination chemistry. Mechanistic studies suggest that the elimination of HCl from the dioxaphospholane intermediate occurs via a two step process involving Grignard reagents and phosphines. The first step involves the addition of a Grignard reagent to one of the carbon atoms adjacent to a phosphorus atom in the dioxaphosphol

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Biosynth
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Chemical properties

Purity:
Min. 95%
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Hazard Info

UN Number:
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