Tetrabromophenol blue

CAS: 4430-25-5

Ref. 3D-FT32314

Product Information

• Name: Tetrabromophenol blue
• Synonyms: TBPBTetrabromophenoltetrabromosulfophthalein3,3?,3?,4,5,5?,5?,6-Octabromophenolsulfonphthalein, 3H-2,1-Benzoxathiole, phenol deriv., 4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromophenol), 4,4′-(4,5,6,7-Tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromophenol], NSC 11236, Phenol, 4,4′-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-, Phenol, 4,4′-(4,5,6,7-tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-, S,S-dioxide, Tetrabromphenol blue, [2,3,4,5-Tetrabromo-6-[(3,5-Dibromo-4-Hydroxy-Phenyl)-(3,5-Dibromo-4-Oxo-Cyclohexa-2,5-Dien-1-Ylidene)Methyl]Phenyl]Sulfonyloxysodium

Description

Tetrabromophenol blue is a model system for the study of the mechanism of action of protein-inhibiting drugs. It has been shown to inhibit cancer cells and human pathogens by binding to basic proteins in the cell membrane, thereby preventing their activity. Tetrabromophenol blue inhibits polymerase chain reaction (PCR) by acting as a competitive inhibitor with respect to DNA, and also inhibits fluorescein angiography by reducing the rate at which dye is taken up by cells. Tetrabromophenol blue binds to wild-type strains of bacteria and halts protein synthesis, but does not bind to mutant strains or human serum. This drug has been shown to be effective against hl-60 cells when used at physiological levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 985.55 g/mol
• Formula: C₁₉H₆Br₈O₅S
• Purity: Min. 95%
• Color/Form: Brown Powder
• InChI: InChI=1S/C19H6Br8O5S/c20-7-1-5(2-8(21)16(7)28)19(6-3-9(22)17(29)10(23)4-6)11-12(24)13(25)14(26)15(27)18(11)33(30,31)32-19/h1-4,28-29H
• InChI key: InChIKey=QPMIVFWZGPTDPN-UHFFFAOYSA-N
• SMILES: O=S1(=O)OC(c2cc(Br)c(O)c(Br)c2)(c2cc(Br)c(O)c(Br)c2)c2c(Br)c(Br)c(Br)c(Br)c21