4-(Trifluoromethoxy)benzenesulfonamide

CAS: 1513-45-7

Ref. 3D-FT32687

Product Information

• Name: 4-(Trifluoromethoxy)benzenesulfonamide
• Synonyms: 4-(Trifluoromethoxy)Benzenesulfonamide, 4-Trifluoromethoxyphenylsulfonamide, 4-[(Trifluoromethyl)oxy]benzenesulfonamide, Benzenesulfonamide, 4-(trifluoromethoxy)-, Benzenesulfonamide, p-(trifluoromethoxy)-

Description

4-(Trifluoromethoxy)benzenesulfonamide is a sulfonamide with anti-fungal and anti-cancer properties. It is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is an enzyme that breaks down the glucagon-like peptide (GLP). This leads to increased GLP levels, which in turn stimulates insulin secretion from the pancreas. 4-(Trifluoromethoxy)benzenesulfonamide has been shown to be toxic to bacterial strains and has been used as an antibiotic for cancer treatment. It also has a fungicidal activity against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, and dermatophytes. The compound is being evaluated in a clinical trial as a treatment for type 2 diabetes mellitus.

• Brand: Biosynth

Chemical properties

• Molecular weight: 241.19 g/mol
• Formula: C₇H₆F₃NO₃S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H6F3NO3S/c8-7(9,10)14-5-1-3-6(4-2-5)15(11,12)13/h1-4H,(H2,11,12,13)
• InChI key: InChIKey=RGOJCHYYBKMRLL-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1ccc(OC(F)(F)F)cc1