Tropolone
CAS: 533-75-5
Ref. 3D-FT34242
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued |
Product Information
- 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-
- 2-Hidroxiciclohepta-2,4,6-Trienona
- 2-Hydroxy-2,4,6-cycloheptatrien-1-one
- 2-Hydroxy-2,4,6-cycloheptatrienone
- 2-Hydroxycyclohepta-2,4,6-Trien-1-One
- 2-Hydroxycyclohepta-2,4,6-Trienone
- 2-Hydroxycyclohepta-2,4,6-trienon
- 2-Hydroxytropone
- Cyclohepta-2,4,6-Trienone, 2-Hydroxy-
- Nsc 89303
- See more synonyms
- Purpurocatechol
- α-Tropolone
Tropolone is a compound that is found in plant species of the genus Myrtus, particularly in M. pomifera and M. rotundifolia. Tropolone has been shown to have anti-inflammatory properties and to inhibit the production of reactive oxygen species (ROS) in vitro. The effect of tropolone on mitochondrial membrane potential was studied in human HL-60 cells and it was found to cause an increase in this parameter.
Molecular modeling studies have revealed the x-ray crystal structures of tropolone and its complex with dioxygen. These structures show that tropolone binds to the heme moiety of cytochrome c oxidase, inhibiting electron transfer reactions in mitochondria. Tropolone also inhibits the synthesis of DNA, RNA, protein, and phospholipids in humans.
