4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

Ref. 3D-FT34370

Product Information

• Name: 4-(Trifluoromethyl)benzyl bromide
• Synonyms: 4-(Bromomethyl)benzotrifluoridea'-Bromo-a,a,a-trifluoro-p-xylene
• Brand: Biosynth
• Description: 4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond.

Chemical properties

• Molecular weight: 239.03 g/mol
• Formula: C₈H₆BrF₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
• InChI key: InChIKey=IKSNDOVDVVPSMA-UHFFFAOYSA-N
• SMILES: FC(F)(F)c1ccc(CBr)cc1