3,4,5-Trimethoxybenzhydrazide

CAS: 3291-03-0

Ref. 3D-FT38137

Product Information

• Name: 3,4,5-Trimethoxybenzhydrazide
• Synonyms: (3,4,5-Trimethoxybenzoyl)hydrazine, 3,4,5-Trimethoxybenzohydrazide, 3,4,5-Trimethoxybenzoic acid hydrazide, 3,4,5-Trimethoxybenzoic hydrazide, 3,4,5-Trimethoxybenzoylhydrazide, Benzoic acid, 3,4,5-trimethoxy-, hydrazide, NSC 39075

Description

3,4,5-Trimethoxybenzhydrazide is an anticancer drug that belongs to the class of acylhydrazones. It has been shown to inhibit the proliferation of tumor cells and induce apoptosis by binding to pBR322 DNA. The molecular docking analysis revealed that this compound binds to nitrogen atoms with a dihedral angle of 180°. This binding results in the formation of a covalent bond between the amine group and the alpha carbon (C=N). 3,4,5-Trimethoxybenzhydrazide is also able to bind with serine protease and glibenclamide. This compound has been shown to have a high uptake rate and a reaction yield of 50%. It also has a viscosity value of 1.2 mPa·s at 25 °C.

• Brand: Biosynth

Chemical properties

• Molecular weight: 226.23 g/mol
• Formula: C₁₀H₁₄N₂O₄
• Purity: Min. 95%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C10H14N2O4/c1-14-7-4-6(10(13)12-11)5-8(15-2)9(7)16-3/h4-5H,11H2,1-3H3,(H,12,13)
• InChI key: InChIKey=KQXHMNUXNHQSOW-UHFFFAOYSA-N
• SMILES: COc1cc(C(=O)NN)cc(OC)c1OC