3-(Trifluoromethyl)phenylacetic acid

CAS: 351-35-9

Ref. 3D-FT46007

Product Information

• Name: 3-(Trifluoromethyl)phenylacetic acid
• Synonyms: (Alpha,Alpha,Alpha-Trifluoro-M-Tolyl)Acetic Acid, (m-Trifluoromethylphenyl)acetic acid, (α,α,α-Trifluoro-m-tolyl)acetic acid, 2-[3-(Trifluoromethyl)phenyl]acetic acid, 3-(Trifluoromethyl)benzeneacetic acid, 3-Trifluoromethyl Phenylacetic Acid, 3-Trifluoromethylbenzeneacetic acid, Acetic acid, (α,α,α-trifluoro-m-tolyl)-, Benzeneacetic acid, 3-(trifluoromethyl)-, [3-(Trifluoromethyl)Phenyl]Acetate, [3-(Trifluoromethyl)Phenyl]Acetic Acid

Description

3-(Trifluoromethyl)phenylacetic acid is an isoquinoline alkaloid that has been found to have anti-inflammatory properties. It was shown to inhibit TNF-α production in mice with colitis, reducing the severity of the disease. 3-(Trifluoromethyl)phenylacetic acid can be administered orally, and it is metabolized reductively by dihydroisoquinoline reductase enzymes. The drug's pharmacokinetics are not well understood, but it is thought to be a substrate for CYP3A4 and P-glycoprotein. 3-(Trifluoromethyl)phenylacetic acid has been studied as a potential antiviral agent and systemic inflammatory response inhibitor.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.15 g/mol
• Formula: C₉H₇F₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H7F3O2/c10-9(11,12)7-3-1-2-6(4-7)5-8(13)14/h1-4H,5H2,(H,13,14)
• InChI key: InChIKey=BLXXCCIBGGBDHI-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1cccc(C(F)(F)F)c1