Tetrahydropyran-3-ylamine

CAS: 120811-32-7

Ref. 3D-FT51320

Product Information

• Name: Tetrahydropyran-3-ylamine
• Synonyms: Tetrahydro-2H-pyran-3-amine hydrochloride, Tetrahydro-Pyran-3-Ylamine, tetrahydro-2H-pyran-3-amine

Description

Tetrahydropyran-3-ylamine is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), an enzyme that plays an important role in the metabolism of proteins. Tetrahydropyran-3-ylamine is used for the treatment of type 2 diabetes and other metabolic disorders. This compound has been shown to inhibit DPP-IV activity in human plasma and in vitro, with IC50 values of 0.6 μM and 0.2 μM respectively. Tetrahydropyran-3-ylamine also inhibits the production of amyloid β peptides, which are associated with Alzheimer's disease. Tetrahydropyran-3-ylamine is orally active and stable at acidic pH levels, making it suitable for oral administration. It has a high degree of crystallinity, with the crystalline substance being thermally stable up to 200°C. Tetrahydropyr

• Brand: Biosynth

Chemical properties

• Molecular weight: 101.15 g/mol
• Formula: C₅H₁₁NO
• Purity: Min. 95%
• InChI: InChI=1S/C5H11NO/c6-5-2-1-3-7-4-5/h5H,1-4,6H2
• InChI key: InChIKey=WUUOEJJGRCQGBQ-UHFFFAOYSA-N
• SMILES: NC1CCCOC1