3-(Trifluoromethyl)phenylboronic acid

CAS: 1423-26-3

Ref. 3D-FT55252

Product Information

• Name: 3-(Trifluoromethyl)phenylboronic acid
• Synonyms: 3-Trifluoromethylboronic acid3-Boronobenzotrifluoride, (3-(Trifluormomethyl)phenyl)boronic acid, 3-(Trifluoromethyl)benzeneboronic acid, 3-Trifluoromethylphenylboronic acid, 3-[(Trifluoromethyl)-Benzene]-Boronic Acid, B-[3-(Trifluoromethyl)phenyl]boronic acid, Boronic acid, B-[3-(trifluoromethyl)phenyl]-, Boronic acid, [3-(trifluoromethyl)phenyl]-, [1-(Trifluoromethyl)phenyl-3-yl]boronic acid, [2-(Trifluoromethyl)Phenyl]Boronic Acid, m-Tolueneboronic acid, α,α,α-trifluoro-

Description

3-(Trifluoromethyl)phenylboronic acid is a potent fatty acid that inhibits the release of TNF-α, a pro-inflammatory cytokine. 3-(Trifluoromethyl)phenylboronic acid binds to the p65 subunit of NF-κB, thereby preventing its activation. This limits the production of reactive oxygen species and neutrophil infiltration in response to LPS-induced lung injury. 3-(Trifluoromethyl)phenylboronic acid also has anti-inflammatory potential, inhibiting the activation of CRTH2 and reducing emissions from diesel engine exhausts. The molecule is homologous to fenofibrate, which belongs to a class of drugs that are used for lowering blood cholesterol. 3-(Trifluoromethyl)phenylboronic acid is not active against life threatening bacterial infections caused by other bacteria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 189.93 g/mol
• Formula: C₇H₆BF₃O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H6BF3O2/c9-7(10,11)5-2-1-3-6(4-5)8(12)13/h1-4,12-13H
• InChI key: InChIKey=WOAORAPRPVIATR-UHFFFAOYSA-N
• SMILES: OB(O)c1cccc(C(F)(F)F)c1