Tri(o-tolyl)phosphine

CAS: 6163-58-2

Ref. 3D-FT60904

Product Information

• Name: Tri(o-tolyl)phosphine
• Synonyms: Tris(2-methylphenyl)phosphine, Intermediate Of Eletriptan And Rizatriptan, Nsc 116667, Phosphine, Tri-O-Tolyl-, Phosphine, tris(2-methylphenyl)-, Phosphorus Tri-O-Tolyl, Totp, Tri(2-Methylphenyl)Phosphine, Tri(O-Tolyl)Phosphine, Tri-2-tolylphosphine, Tri-O-Tolylphosphine, Tri-O-Tolyphosphine, Tri-Ortho-Tolylphosphine, Tris(2-Methylphenyl)-Phosphin, Tris(2-Methylphenyl)Phosphane, Tris(2-Metilfenil)Fosfina, Tris(2-Tolyl)Phosphine, Tris(2-toluene)phosphine, Tris(O-Tolyl)Phosphine, Tris(o-methylphenyl)phosphine, Tris-o-tolyphosphine

Description

Tri(o-tolyl)phosphine is a phosphine ligand that is used in palladium-catalyzed coupling reactions. It also binds to copper to form a catalyst for the hydrolysis of esters. Tri(o-tolyl)phosphine has been shown to inhibit the activity of cholesterol esterase, an enzyme involved in fat metabolism, and can be used as a treatment for obesity. This drug has also been shown to have immunological effects on lymphocyte transformation and antibody response. The phosphine ligand can bind with fatty acids and cholesterol esters, which are associated with inflammatory disorders such as atherosclerosis, Alzheimer's disease, and Parkinson's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 304.37 g/mol
• Formula: C₂₁H₂₁P
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C21H21P/c1-16-10-4-7-13-19(16)22(20-14-8-5-11-17(20)2)21-15-9-6-12-18(21)3/h4-15H,1-3H3
• InChI key: InChIKey=COIOYMYWGDAQPM-UHFFFAOYSA-N
• SMILES: Cc1ccccc1P(c1ccccc1C)c1ccccc1C