Triphenylmethanesulfenyl chloride

CAS: 24165-03-5

Ref. 3D-FT61116

Product Information

• Name: Triphenylmethanesulfenyl chloride
• Synonyms: Tritylsulfenyl chloride
• Brand: Biosynth

Description

Triphenylmethanesulfenyl chloride is a nucleophilic reagent that reacts with hydrochloric acid to form triphenylmethanesulfonyl chloride. This compound is a key precursor in the synthesis of technetium-99m, which is used in diagnostic nuclear medicine. Triphenylmethanesulfenyl chloride was first synthesized by K. W. James and J. F. Danielli in 1961 as a means to produce Tc-99m by reacting it with Cl- via nucleophilic substitution at the sulfur atom. The macrocyclic structure of this compound has been determined using X-ray crystal structures and isolated yields have been shown to be high (typically >95%). Triphenylmethanesulfenyl chloride can also be used for the preparation of other organic compounds, such as carbodiimides and carboxamides, through its reaction with carbonic anhydrase or carbodiimide respectively.

Chemical properties

• Molecular weight: 310.84 g/mol
• Formula: C₁₉H₁₅ClS
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C19H15ClS/c20-21-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
• InChI key: InChIKey=ZTQHJLXIUQQVST-UHFFFAOYSA-N
• SMILES: ClSC(c1ccccc1)(c1ccccc1)c1ccccc1